Indirect measurement of specific activity of [11C]CO2 and the effects of target volume fractionation
Indirect measurement of specific activity of [11C]CO2 and the effects of target volume fractionation
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[11C]CO2 比活度的间接测量和目标体积分级的影响
DOI：
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
J. Koziorowski
中科院分区：
文献类型：
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作者：
J. Fonslet;O. Itsenko;J. Koziorowski
为了确定[11 C]CO2的比活度并检查冷碳在目标和输送管线中的分布，我们尝试进行易于实现的一步反应，允许使用配备有UV检测器的HPLC进行检测。不幸的是，这证明是一项比我们想象的更困难的任务。在这项工作中合成的有机锂化合物，是太多的反应性产生可重复的结果，因此没有目标体积分馏数据是在这一点上。
In order to determine the specific activity of [11C]CO2 and examine the distribution of cold carbon in target and delivery lines, we attempted to make an easily accessible, one-step reaction, allowing detection using HPLC equipped with UV detector. Unfortunately this proved a more difficult task than we imagined. The organolithium compounds synthesised in this work, were much too reactive to yield reproducible results, and thus no target volume fractionation data are available at this point.