High prevalence of glycopeptide resistance genes vanB, vanD, and vanG not associated with enterococci in human fecal flora

High prevalence of glycopeptide resistance genes vanB, vanD, and vanG not associated with enterococci in human fecal flora
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DOI:
10.1128/aac.49.11.4784-4786.2005
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发表时间:
2005-11-01
影响因子:
4.9
通讯作者:
Bergeron, MG
Bergeron, MG
中科院分区:
医学2区
文献类型:
--
作者:
Domingo, MC;Huletsky, A;Bergeron, MG

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在两家医院使用 PCR 技术对直肠拭子中肠球菌相关万古霉素耐药基因 vanA、vanB、vanD、vanE 和 vanG 的存在进行了调查。所有检测到的 vanA 基因均与耐万古霉素肠球菌 (VRE) 相关,而与 VRE 相关的 vanB 基因仅在一家医院检测到 (4.7%)。然而,在两家医院中,发现与肠球菌无关的vanB(6.2%和2.3%)、vanD(43.8%和26.7%)和vanG(10.5%和6.9%)基因的患病率较高。
The presence of Enterococcus-associated vancomycin resistance genes vanA, vanB, vanD, vanE, and vanG in rectal swabs was investigated in two hospitals using PCR. All vanA genes detected were associated with vancomycin-resistant enterococci (VRE), whereas VRE-associated vanB genes were detected in only one hospital (4.7%). However, in both hospitals, high prevalences of vanB (6.2 and 2.3%), vanD (43.8 and 26.7%), and vanG (10.5 and 6.9%) genes not associated with enterococci were found.