ADPr-ChAP: Mapping ADP-Ribosylation onto the Genome.
ADPr-ChAP: Mapping ADP-Ribosylation onto the Genome.
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ADPr-ChAP:将 ADP-核糖基化映射到基因组上。
DOI:
10.1016/j.molcel.2016.01.023
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发表时间:
2016
期刊:
影响因子:
16
通讯作者:
Leung,AnthonyKL
中科院分区:
文献类型:
--
作者:
McPherson,RobertLyle;Leung,AnthonyKL
In this issue ofMolecular Cell, Bartolomei et al. (2016) describe a chromatin affinity precipitation method using well-characterized ADP-ribose binding domains to provide the first genome-wide view of ADP-ribosylated chromatin. Here, we discuss its potential applications and the remaining challenges ahead.