Alcohol and hypertension: new insights from population studies.
Alcohol and hypertension: new insights from population studies.
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酒精和高血压：人口研究的新见解。
DOI：
10.1093/eurheartj/8.suppl_b.19
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发表时间：
1987
影响因子：
39.3
通讯作者：
Criqui,MH
中科院分区：
文献类型：
--
作者：
Criqui,MH
酒精和血压之间的联系现在已经得到了很好的证实。某些亚群，如老年人，白人，也许是男性，可能是在酒精升压效应的易感性增加，虽然在升压反应可能存在相当大的个体差异。一个阈值可能存在于每天两杯左右，但一些研究报告了不同的阈值或更多的线性关系。迄今为止的证据表明，乙醇，而不是酒精饮料的其他成分或相关行为，会使血压升高。迄今为止的数据可能与戒断假说最一致，但此时不能排除直接的升压效应。无论机制如何，升压效应似乎是完全可逆的。最后，现有的证据表明，酒精引起的高血压确实会导致常见的高血压后遗症。
The link between alcohol and blood pressure is now well established. Certain subsets, such as older persons, whites and perhaps men may be at increased susceptibility to an alcohol pressor effect, although considerable interindividual variation in the pressor response probably exists. A threshold may exist at around two drinks per day, but several studies report either different thresholds or more linear relationships. The evidence to date suggests that ethanol, rather than some other constituent of alcoholic beverages or an associated behavior, raises blood pressure.The data available to date are perhaps most compatible with a withdrawal hypothesis, but a straightforward pressor effect cannot be excluded at this time. Whatever the mechanism, the pressor effect appears to be fully reversible. Finally, the available evidence suggests that alcohol induced hypertension will indeed lead to the usual hypertensive sequalae.