Persistent increase in the incidence of abdominal aortic aneurysm in Scotland, 1981-2000

Persistent increase in the incidence of abdominal aortic aneurysm in Scotland, 1981-2000
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DOI:
10.1002/bjs.4342
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发表时间:
2003-12-01
影响因子:
9.6
通讯作者:
Fowkes, FGR
Fowkes, FGR
中科院分区:
医学1区
文献类型:
--
作者:
Best, VA;Price, JF;Fowkes, FGR

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背景:在20世纪70年代和80年代,腹主动脉瘤(AAA)的死亡率和发病率在整个发达国家都有所增加。由于AAA与其他心血管疾病,最近发病率下降的危险因素类似,AAA的发病率应表现出类似的下降趋势。方法:收集的数据,获得所有的主动脉瘤的主要诊断,导致死亡或出院在苏格兰1981年和2000年之间。根据性别和年龄,动脉瘤的网站和类型的医院acceptance.Results:在1981年至2000年,42.3%的10 822例死亡的主动脉瘤在苏格兰的趋势进行了分析,归因于腹主动脉。AAA的死亡率从1981年的2.62/10万增加到2000年的6.82/10万,增加了2.6倍。AAA的住院率也上升了三倍,增加了择期入院(从3.05至7.80每100 000)和急诊入院(从7.44至11.23每100 000)。这不太可能仅仅是由于检测和诊断的变化、数据不准确、编码或人口老龄化。择期和急诊AAA入院的发生率增加,表明AAA的发生率可能发生了真正的持续上升。
Background: In the 1970s and 1980s, mortality and morbidity rates for abdominal aortic aneurysm (AAA) increased throughout the developed world. As AAAs are associated with similar risk factors to other cardiovascular diseases that have recently decreased in incidence, the incidence of AAA should show a similar declining trend.Methods: Routinely collected data were obtained on all primary diagnoses of aortic aneurysm resulting in death or hospital discharge in Scotland between 1981 and 2000. Trends in the data were analysed according to sex and age, aneurysm site and type of hospital admission.Results: Between 1981 and 2000, 42.3 per cent of the 10 822 deaths from aortic aneurysm in Scotland were attributed to the abdominal aorta. Age-adjusted mortality rates for AAA increased 2.6-fold from 2.62 deaths per 100000 in 1981 to 6.82 per 100000 in 2000. Hospital admissions for AAA also rose threefold, with increases in both elective admissions (from 3.05 to 7.80 per 100 000) and emergency admissions (from 7.44 to 11.23 per 100 000).Conclusion: The incidence of AAA has increased over the past 20 years in Scotland. This is unlikely to be due simply to changes in detection and diagnosis, data inaccuracies, coding or ageing of the population. The incidence of both elective and emergency admission for AAA increased, suggesting that a genuine and persistent rise in the incidence of AAA has probably occurred.