Right lobe living donor liver transplantation: A review

Right lobe living donor liver transplantation: A review
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右叶活体肝移植:综述

DOI:
10.1002/lt.500060117
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发表时间:
2000
影响因子:
4.6
通讯作者:
A. Marcos
A. Marcos
中科院分区:
医学2区
文献类型:
--
作者:
A. Marcos

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成人移植受者器官的持续短缺激发了人们对成人活体肝移植(LDLT)的热情。主要关注的是能否切除足够大小的移植物而不使供体面临过度的风险。肝右叶通常对于成年受者来说足够大,但由于右叶 (RL) 切除术的真实和感知风险,外科医生一直犹豫是否向患者提供这种选择。 1999 年报道了第一批 RL 切除术,其中包括大量患者,结果令人鼓舞。捐赠者只出现了轻微的并发症,接受者的情况也很好。人们对这些供体切除术的热情日益高涨,越来越多的中心开始进行此类手术。全球在儿科 LDLT 方面有大量经验,但在成人方面却很少,而且针对这一人群有独特的考虑因素。本次审查审查了成年受赠者的捐赠者选择标准,强调了对良好结果至关重要的技术要点,并检查了捐赠者和受赠者的早期结果和并发症。如果初步结果继续重现,RL LDLT 可能会对日益恶化的器官短缺产生重大影响。
The continuing shortage of organs for adult transplant recipients has generated enthusiasm for adult‐to‐adult living donor liver transplantation (LDLT). The major concern has been the ability to resect a graft of adequate size without subjecting the donor to undue risk. The right hepatic lobe is generally large enough for adult recipients, but because of the real and perceived risks of right lobe (RL) resection, surgeons have been hesitant to offer this option to their patients. The first series of RL resections that included a significant number of patients was reported in 1999, and the results were encouraging. Only minor complications occurred in donors, and the recipients fared quite well. Enthusiasm for these donor resections is growing, and more centers are beginning to perform them. There is a good deal of global experience with pediatric LDLT but little with adults, and there are unique considerations in this population. This review examines donor selection criteria for adult recipients, highlights technical points critical for good outcome, and examines the early results and complications in both donors and recipients. If the preliminary results continue to be reproduced, RL LDLT could have significant impact on the worsening organ shortage.
DOI: 10.1097/00000658-199906000-00005
发表时间: 1999-06-01
期刊: ANNALS OF SURGERY
影响因子: 9
作者:
Fong, YM;Sun, RL;Blumgart, LH
通讯作者: Blumgart, LH