Case of primary localized cutaneous amyloidosis with protean clinical manifestations: Lichen, poikiloderma-like, dyschromic and bullous variants
Case of primary localized cutaneous amyloidosis with protean clinical manifestations: Lichen, poikiloderma-like, dyschromic and bullous variants
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DOI：
10.1111/j.1346-8138.2011.01254.x
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发表时间：
2011-11-01
影响因子：
3.1
通讯作者：
Goh, Chee-Leok
中科院分区：
文献类型：
--
作者：
Chandran, Nisha Suyien;Goh, Boon-Kee;Goh, Chee-Leok
原发性局限性皮肤淀粉样变性（PLCA）通常表现为黄斑和地衣变异体。我们报告了一位27岁的中国女性，她的皮肤特征是罕见的皮损样，不变色和大泡型PLCA，以及常见的地衣变体。没有综合征相关性或系统性累及，各种形态亚型彼此孤立发生。我们回顾了PLCA的临床谱，强调了该患者的多种临床表现，并讨论了其与组织病理学特征相关的假设发病机制。
Primary localized cutaneous amyloidosis (PLCA) commonly presents as macular and lichen variants. We present a case of a 27-year-old Chinese woman with cutaneous features of the rarely reported poikiloderma-like, dyschromic and bullous forms of PLCA, and the commoner lichen variant. There were no syndromic associations or systemic involvement, and the various morphological subtypes occurred in isolation from one another. We review the clinical spectrum of PLCA, highlight its protean clinical manifestations in this patient, and discuss its postulated pathogenesis in relation to its histopathological features.