Computational life sciences II
Computational life sciences II
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计算生命科学II
DOI：
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
I. Fischer
中科院分区：
文献类型：
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作者：
M. Berthold;R. Glen;K. Diederichs;O. Kohlbacher;I. Fischer
系统生物学。-结构蛋白相互作用预测激酶抑制剂在胰腺肿瘤基因表达上调中的相互作用。-基于特征挖掘的生化途径分析。-逆向工程基因调控相互作用的递归神经模糊网络模型。-数据分析和集成。虚拟点散射体在大分子x射线晶体学中的一些应用。- BioRegistry：生物信息学数据库的结构化元数据存储库。鲁棒Perron聚类分析在计算生命科学中的各种应用。-结构生物学。-三维蛋白质结构的多重排列。-二级结构比对（PASSTA）蛋白质注释。- MAPPIS：蛋白质-蛋白质界面的多重3D对齐。——基因组学。-基因组分析的频繁项目集。-基于支持向量机灵敏度分析的基因选择。-纤毛虫的断点图。-计算蛋白质组学。-展望：一个R包分析SELDI测量鉴定蛋白质生物标志物。-复杂蛋白质组学样本中诊断标记的自动绝对定量算法。-晶体中蛋白质组装的检测。-分子信息学。-使用COSMO筛选电荷（COSMO/3PP）进行分子相似性搜索。-增加芯片筛选的多样性和目标灵活性。-药物大小分子的多个半柔性三维叠加。-分子结构测定和模拟。-求解粗势Smoluchowski方程的效率考虑。-渐进式拉格朗日优化快速准确的RNA结构比对。-利用动态密度混合模型对分子构象进行可视化分析。-分布式数据挖掘。—网格计算环境下的分布式BLAST。-大型和不平衡数据集的支持向量机器学习参数并行调优。酵母中蛋白质组学网络的结构。
Systems Biology.- Structural Protein Interactions Predict Kinase-Inhibitor Interactions in Upregulated Pancreas Tumour Genes Expression Data.- Biochemical Pathway Analysis via Signature Mining.- Recurrent Neuro-fuzzy Network Models for Reverse Engineering Gene Regulatory Interactions.- Data Analysis and Integration.- Some Applications of Dummy Point Scatterers for Phasing in Macromolecular X-Ray Crystallography.- BioRegistry: A Structured Metadata Repository for Bioinformatic Databases.- Robust Perron Cluster Analysis for Various Applications in Computational Life Science.- Structural Biology.- Multiple Alignment of Protein Structures in Three Dimensions.- Protein Annotation by Secondary Structure Based Alignments (PASSTA).- MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces.- Genomics.- Frequent Itemsets for Genomic Profiling.- Gene Selection Through Sensitivity Analysis of Support Vector Machines.- The Breakpoint Graph in Ciliates.- Computational Proteomics.- ProSpect: An R Package for Analyzing SELDI Measurements Identifying Protein Biomarkers.- Algorithms for the Automated Absolute Quantification of Diagnostic Markers in Complex Proteomics Samples.- Detection of Protein Assemblies in Crystals.- Molecular Informatics.- Molecular Similarity Searching Using COSMO Screening Charges (COSMO/3PP).- Increasing Diversity in In-silico Screening with Target Flexibility.- Multiple Semi-flexible 3D Superposition of Drug-Sized Molecules.- Molecular Structure Determination and Simulation.- Efficiency Considerations in Solving Smoluchowski Equations for Rough Potentials.- Fast and Accurate Structural RNA Alignment by Progressive Lagrangian Optimization.- Visual Analysis of Molecular Conformations by Means of a Dynamic Density Mixture Model.- Distributed Data Mining.- Distributed BLAST in a Grid Computing Context.- Parallel Tuning of Support Vector Machine Learning Parameters for Large and Unbalanced Data Sets.- The Architecture of a Proteomic Network in the Yeast.