[Language Symptoms of Alzheimer's Disease].
[Language Symptoms of Alzheimer's Disease].
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DOI：
10.11477/mf.1416200437
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发表时间：
2016-05-01
期刊：
影响因子：
--
通讯作者：
Shinagawa, Shunichiro
中科院分区：
文献类型：
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作者：
Shinagawa, Shunichiro
阿尔茨海默病(AD)是一种以进行性记忆障碍为主要特征的神经退行性疾病。语言症状被认为不是疾病特异性的，因此直到最近才引起许多研究人员的兴趣。典型的AD患者在疾病早期表现为健忘性失语，然后是经皮质感觉性失语；然而，他们的语言症状是不同的。最近，对数变异的原发性进行性失语症(PPA)的概念被提出，据报道有阿尔茨海默病的神经病理。临床医生应该验证患者的语言能力，因为语言可能是揭示他们真实认知功能的关键。
Alzheimer's disease (AD) is a neurodegenerative disorder mainly characterized by progressive memory disturbance. Language symptoms are considered to be less disease specific and therefore did not attract many researchers, interest until recently. Typical patients with AD present amnesic aphasia in the early disease stage followed by transcortical sensory aphasia; however, their language symptoms are varied. Recently, the concept of logopenic variant of primary progressive aphasia (PPA) has been developed, which is reported to have Alzheimer's neuropathology. Clinicians should verify patients' language abilities, as language can be the key to reveal their true cognitive functions.