Principles and limitations of NMR diffusion measurements.
Principles and limitations of NMR diffusion measurements.
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DOI：
10.4103/0971-6203.31148
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发表时间：
2007-01
影响因子：
0.9
通讯作者：
Guilfoyle DN
中科院分区：
文献类型：
--
作者：
Hrabe J;Kaur G;Guilfoyle DN
扩散光谱、成像，特别是扩散张量成像因其广泛的临床和研究应用而变得流行起来，这些应用范围从中风评估到纤维追踪。除了少数例外，这些方法植根于扩散衰减信号的经典Stejskal-Tanner公式，通常通过求解Bloch-Torrey偏微分方程组获得。在这里，我们以最简单的方式推导出Stejskal-Tanner公式，避免了积分和微分方程。这种方法可以很容易地了解扩散信号衰减的来源，各种扩散序列参数的影响，以及许多重要的陷阱，这些将在最后一节进行讨论。
Diffusion spectroscopy, imaging and particularly diffusion tensor imaging have become popular thanks to their numerous clinical and research applications which span from brain stroke evaluation to fiber tracking. With a few exceptions, these methods are rooted in the classic Stejskal-Tanner formula for the diffusion-attenuated signal, usually obtained by solving the Bloch-Torrey partial differential equations. Here we derive the Stejskal-Tanner formula in the simplest possible manner, avoiding integrals and differential equations. This approach makes it easy to understand the origin of the diffusion signal attenuation, the effects of various diffusion sequence parameters, and also the numerous important pitfalls, which are discussed in the last section.