Prevalence of rheumatoid arthritis in Italy: The Chiavari study
Prevalence of rheumatoid arthritis in Italy: The Chiavari study
复制标题
DOI：
10.1136/ard.57.5.315
复制
发表时间：
1998-05-01
影响因子：
27.4
通讯作者：
Accardo, S
中科院分区：
文献类型：
--
作者：
Cimmino, MA;Parisi, M;Accardo, S
为了确定类风湿性关节炎（RA）在意大利一般population. Methods的患病率进行了研究，在1991-92年在基亚瓦里，位于利古里亚海岸的一个小镇，并涉及4456名受试者年龄在16岁或以上，从四个一般的做法。受试者收到一份邮寄问卷，用于检测当前或过去患有炎性关节疾病的患者。样本的年龄和性别分布与1992年人口普查的意大利人口相似。由风湿病学家对报告至少一对对称关节有关节肿胀病史的患者进行审查。无应答者和应答者谁没有参加clinic.Results的临床记录4456（73.9%）的受试者回答了问卷。3294名应答者的平均（SD）年龄为48.3（19.3）岁;其中53.7%为女性。230例受试者（7%）报告了至少两个对称关节肿胀。其中，11例患者符合1987年ARA标准的RA。RA患病率为0.33%（95% CI 0.13，0.53）在一般人群中，0.13%男性（95% CI 0，0.31）和0.51%（95% CI 0.18，0.84）。这些数据与50年代意大利文献中发表的三项早期研究的结果一致，并证实了RA在意大利较低，在过去40年中保持不变。
Objective-To ascertain the prevalence of rheumatoid arthritis (RA) in an Italian general population.Methods-The study was performed in the years 1991-92 in Chiavari, a small town located on the Ligurian coast, and involved 4456 subjects aged 16 years or more from four general practices. The subjects received a postal questionnaire developed to detect patients with current or past inflammatory joint diseases. The age and sex distribution of the sample were similar to those of the Italian population from the 1992 census. Patients reporting a history of joint swelling in at least a pair of symmetrical joints were reviewed by a rheumatologist. The clinical records of non-responders and responders who failed to attend the clinic were also reviewed.Results-3294 of 4456 (73.9%) subjects answered to the questionnaire. The mean (SD) age of the 3294 responders was 48.3 (19.3) years; 53.7% of them were female. Swelling in at least two symmetrical joints was reported by 230 subjects (7%). Among them, 11 patients fulfilling the 1987 ARA criteria for RA.were identified. The prevalence of RA was 0.33% (95% CI 0.13, 0.53) in the general population, 0.13% (95% CI 0, 0.31) in men, and 0.51% (95% CI 0.18, 0.84) in women.Conclusions-These data are consistent with the results of three earlier studies published in the fifties in the Italian literature and confirm that the prevalence of RA is low in Italy and has remained unchanged in the last 40 years.