Dysfunction of subtelomeric methylation and telomere length in gallstone disease and gallbladder cancer patients of North Central India

Dysfunction of subtelomeric methylation and telomere length in gallstone disease and gallbladder cancer patients of North Central India
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印度中北部胆结石病和胆囊癌患者的亚端粒甲基化和端粒长度功能障碍

DOI:
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发表时间:
2016
影响因子:
3
通讯作者:
Pramod K. Tiwari
Pramod K. Tiwari
中科院分区:
医学4区
文献类型:
--
作者:
S. Poojary;G. Mishra;Sanjiv Gupta;B. Shrivastav;Pramod K. Tiwari

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端粒在癌症进展中起重要作用。最近,已经表明,亚电体甲基化对包括癌症在内的各种疾病中的端粒长度负面调节。在这里,我们评估了胆囊癌(GBC)中亚电体甲基化在端粒功能障碍中的影响,以及该功能障碍是否受胆结石的影响影响。
Telomeres play an important role in cancer progression. Recently it has been shown that subtelomeric methylation negatively regulates telomere length in various diseases, including cancers. Here, we evaluated the influence of subtelomeric methylation in telomere dysfunction in gallbladder cancer (GBC), and whether this dysfunction is affected by the presence of gallstones.
DOI: --
发表时间: 1995-06
期刊: Cancer research
影响因子: 11.2
作者:
I. Wistuba;K. Sugio;J. Hung;Y. Kishimoto;A. Virmani;I. Roá;J. Albores–Saavedra;A. Gazdar
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