Reproducibility of sonographic assessment of fetal liver length in diabetic pregnancies
Reproducibility of sonographic assessment of fetal liver length in diabetic pregnancies
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DOI：
10.1002/uog.5298
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发表时间：
2008-05-01
影响因子：
7.1
通讯作者：
McEwing, R.
中科院分区：
文献类型：
--
作者：
Anderson, N. G.;Notley, E.;McEwing, R.
目的测定胎儿肝脏大小，对监测妊娠期糖尿病治疗效果有一定意义。我们的目的是评估胎儿肝脏长度测量的重复性在妊娠妇女diabetes.Methods从2006年4月3日至2006年12月5日，我们评估了观察者和观察者之间的变化胎儿肝脏长度测量的SS超声波在44名孕妇糖尿病，其中34人有妊娠期糖尿病。母亲的平均年龄为33岁，母亲的平均体重为92 kg，平均体重指数（BMI）为33.7 kg/m（2）。通过计算观察者内SD比值评估协变量BMI、孕龄和母亲年龄对胎肝长度重复性的影响。我们比较了肝脏长度与腹围和胎龄。12名超声医师中的9名平均扫描6名女性（范围，3-12）作为第一超声医师，所有12名超声医师平均扫描4名女性（范围，1-10）作为第二超声医师。结果胎儿肝脏长度的测量具有良好的重复性。观察者内SD为3.06（95% CI，2.68-3.59）mm;观察者间SD为2.17（95% CI，0.59-4.83）mm;观察者内相关性为0.77（95% CI，0.63-0.87），观察者间相关性为0.84（95% CI，0.51-0.99）。协变量的影响是最小的，SD为1个单位增加的协变量为1.06胎龄，体重指数为0.98，和0.97产妇年龄。结论测量胎儿肝脏长度在糖尿病妊娠是可重复的。作为监测妊娠期糖尿病治疗效果的指标值得进一步研究。版权所有（C）2008 ISUOG.由John Wiley & Sons有限公司出版
Objectives Assessing fetal liver size might be useful in monitoring the effectiveness of the treatment of diabetes in pregnancy. We aimed to assess the reproducibility of fetal liver-length measurement in pregnant women with diabetes.Methods From 3 April 2006 to 5 December 2006, we assessed intraobserver and interobserver variation of fetal liver-length measurements on SS sonograms in 44 pregnant women with diabetes, 34 of whom had gestational diabetes. The mean maternal age was 33 years, the mean maternal weight was 92 kg and the mean body mass index (BMI) was 33.7 kg/m(2). The effect of covariates BMI, gestational age and maternal age on the reproducibility of fetal liver length was assessed by calculating intraobserver SD ratios. We compared liver length with abdominal circumference and gestational age. Nine of 12 sonographers scanned, on average, six women (range, 3-12) as the first sonographer, and all 12 sonographers scanned, on average, four women (range, 1-10) as the second sonographer. The data were analyzed using a hierarchical linear model.Results Measurement of fetal liver length was reproducible. The intraobserver SD was 3.06 (95% CI, 2.68-3.59) mm; the interobserver SD was 2.17 (95% CI, 0.59-4.83) mm; the intraobserver correlation was 0.77 (95% CI, 0.63-0.87), and the interobserver correlation was 0.84 (95% CI, 0.51-0.99). The covariate effects were minimal, the SD for a 1-unit increase in the covariate was 1.06 for gestational age, 0.98 for BMI, and 0.97 for maternal age.Conclusions Measurement of fetal liver length in the diabetic pregnancy is reproducible. It is worthy of further investigation as a parameter for monitoring the effectiveness of treatment of the diabetic pregnancy. Copyright (C) 2008 ISUOG. Published by John Wiley & Sons, Ltd.