Neuronal cadherins: The keys that unlock layer-specific astrocyte identity?
Neuronal cadherins: The keys that unlock layer-specific astrocyte identity?
复制标题
神经元钙粘蛋白：解锁层特异性星形胶质细胞身份的钥匙？
DOI：
10.1083/jcb.202309050
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Ackerman,SarahD
中科院分区：
文献类型：
--
作者：
Jetter,Haley;Ackerman,SarahD
星形胶质细胞错综复杂的形态对于正常的大脑功能是必不可少的，但设定星形胶质细胞形态的内在和外在线索在很大程度上是未知的。在这一期中，Tan等人。(https://doi.org/10.1083/jcb.202303138)显示，神经元钙粘附素的层特异性表达局部调节星形胶质细胞的形态发生和异质性。
An astrocyte’s intricate morphology is essential for proper brain function, but the intrinsic and extrinsic cues that set astrocyte morphology are largely unknown. In this issue, Tan et al. (https://doi.org/10.1083/jcb.202303138) show that layer-specific expression of neuronal cadherins locally regulates astrocyte morphogenesis and heterogeneity.