Toward a miniaturized mechanical surgeon
Toward a miniaturized mechanical surgeon
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DOI：
10.1016/s1369-7021(09)70272-x
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发表时间：
2009-10-01
期刊：
影响因子：
24.2
通讯作者：
Gracias, David H.
中科院分区：
文献类型：
--
作者：
Fernandes, Rohan;Gracias, David H.
亚毫米级工程的最新进展表明，构建用于活体诊断和治疗的微型无绳索医疗工具是可能的。我们回顾了与小型、远程控制或自主手术设备的设计和实施相关的挑战。两个关键的里程碑是创造具有化学、机械和电子功能的宏观外科设备的微型模拟；以及控制它们或使其能够独立决策的无线策略(自主驱动)。我们总结了在这一领域取得的初步成果，并讨论了可能的解决方案，重点是材料科学和工程领域的创新可以应对的挑战。
Recent advances in sub-millimeter scale engineering suggest the possibility for constructing miniaturized tetherless medical tools for in vivo diagnostics and therapeutics. We review the challenges associated with the design and implementation of small, remotely controlled or autonomous surgical devices. Two key milestones are the creation of tiny mimics of macroscopic surgical devices with chemical, mechanical and electronic functionalities; and wireless strategies to control them or enable independent decision making (autonomous actuation). We summarize early results obtained in this area and discuss possible solutions with a focus on the challenges that can be addressed by innovations in materials science and engineering.