Diagnostic efficiency of neuropsychological test scores for discriminating boys with and without attention deficit-hyperactivity disorder
Diagnostic efficiency of neuropsychological test scores for discriminating boys with and without attention deficit-hyperactivity disorder
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DOI：
10.1037/0022-006x.68.3.477
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发表时间：
2000-06-01
影响因子：
5.9
通讯作者：
Faraone, SV
中科院分区：
文献类型：
--
作者：
Doyle, AE;Biederman, J;Faraone, SV
越来越多的文献记录了有和没有注意力缺陷多动障碍（ADHD）的男孩之间的神经心理休息的群体差异;然而，这种测试是否可以区分患有ADHD的个体与非ADHD对照仍不清楚。本研究采用条件概率和接收器操作特性分析，以检查效率最少为基础的诊断歧视在一个大样本的男孩与不ADHD的参考。单一的神经心理学测试在不同的临界分数有有限的辨别能力。当多个测试一起使用时，ADHD状态的预测得到改善，但总体诊断效率仍然有限，诊断效率没有显着差异时，药物和非药物指数儿童分别考虑。结果表明，ADHD儿童在注意力和执行功能的神经心理学测试中表现出不同的缺陷。多项神经心理学测试的损伤可以预测ADHD，但正常的分数并不能排除诊断。ADHD儿童神经心理学缺陷的预后影响需要进一步研究。
A growing literature has documented group differences between boys with and without attention deficit-hyperactivity disorder (ADHD) on neuropsychological rests; however, whether or not such tests can discriminate individuals with ADHD from non-ADHD controls remains unclear. This study used conditional probability and receiver operating characteristic analyses to examine the efficiency of lest-based diagnostic discriminations in a large sample of referred boys with and without ADHD. Single neuropsychological tests had limited discriminating ability at various cutoff scores. When multiple tests were used together, prediction of ADHD status improved but overall diagnostic efficiency remained limited, Diagnostic efficiency did not differ when medicated and nonmedicated index children were considered separately. Results suggest that children with ADHD show variable deficits on neuropsychological tests of attention and executive functions. Impairments on multiple neuropsychological tests are predictive of ADHD, but normal scores do not rule out the diagnosis. The prognostic implications of variable neuropsychological deficits in children with ADHD require further investigation.