GALACTOSYLSUCROSE AND XYLOSYLFRUCTOSIDE ALTER DIGESTIVE-TRACT SIZE AND CONCENTRATIONS OF CECAL ORGANIC-ACIDS IN FLATS FED DIETS CONTAINING CHOLESTEROL AND CHOLIC-ACID
GALACTOSYLSUCROSE AND XYLOSYLFRUCTOSIDE ALTER DIGESTIVE-TRACT SIZE AND CONCENTRATIONS OF CECAL ORGANIC-ACIDS IN FLATS FED DIETS CONTAINING CHOLESTEROL AND CHOLIC-ACID
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DOI：
10.1093/jn/124.1.52
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发表时间：
1994-01-01
影响因子：
4.2
通讯作者：
KIMURA, S
中科院分区：
文献类型：
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作者：
HOSHI, S;SAKATA, T;KIMURA, S
在喂食富含胆固醇的无纤维饮食[胆固醇6 +胆酸1.5（g/kg）]的大鼠中，比较半乳糖基蔗糖和木糖基果糖苷对体重增加、消化道质量和盲肠中有机酸如乙酸、丙酸、丁酸、乳酸和琥珀酸浓度的影响，所述饮食含有半乳糖基蔗糖、木糖基果糖苷或蔗糖（100 g/kg）或上述不含试验糖的无纤维饲料（对照）21 d。与对照组大鼠相比，喂食蔗糖的大鼠体重增加更大，但喂食半乳糖基蔗糖或木糖基果糖的大鼠体重增加不明显。质量的小肠和结肠加直肠的大鼠喂木糖基果糖苷比对照组大鼠。与对照组相比，饲粮中添加木糖基果糖苷的大鼠盲肠内容物和盲肠组织质量较重，盲肠内容物含水量较高，盲肠内容物pH和氨浓度较低。半乳糖基蔗糖具有类似的效果，尽管并非所有差异都是显著的。盲肠浓度中氢离子浓度与盲肠总有机酸浓度和盲肠内容物量呈正相关。盲肠内容物中测得的有机酸总浓度与盲肠组织质量呈正相关。半乳糖基蔗糖、木糖基果糖苷和蔗糖对体重沉积的估计贡献分别为0.19、-0.29和0.51（g体重增加/g糖）。
Influences of galactosylsucrose and xylosylfructoside on body mass gain, the digestive tract mass and concentrations of organic acids such as acetic, propionic, butyric, lactic and succinic acid in the cecum were compared among rats fed a cholesterol-enriched fiber-free diet [cholesterol 6 + cholic acid 1.5 (g/kg)] containing either galactosylsucrose, xylosylfructoside or sucrose (100 g/kg) or the above fiber-free diet without test sugar (control) for 21 d. Body mass gain was greater in rats fed sucrose, but not in rats fed galactosylsucrose or xylosylfructoside, than in control rats. The mass of the small intestine and colon plus rectum was larger in rats fed xylosylfructoside than in control rats. Cecal contents and cecal tissue mass were heavier, water content of cecal contents was higher, and pH and ammonia concentration of cecal contents were lower in rats fed diets containing xylosylfructoside than in control rats. Galactosylsucrose had similar effects, although not all differences were significant. The concentration of hydrogen ion in cecal concentration positively correlated to total cecal concentration of measured organic acids and to amount of cecal contents. Total concentration of measured organic acids in cecal contents positively correlated to cecal tissue mass. The estimated contribution of galactosylsucrose, xylosylfructoside and sucrose for body mass deposition were 0.19, -0.29 and 0.51 (g body mass gained/g sugar), respectively.