Sensitivity of multiple damage parameters to compressive overload in cortical bone
Sensitivity of multiple damage parameters to compressive overload in cortical bone
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DOI：
10.1115/1.1933916
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发表时间：
2005-08-01
影响因子：
1.7
通讯作者：
Keaveny, TM
中科院分区：
文献类型：
--
作者：
Morgan, EF;Lee, JJ;Keaveny, TM
损伤积累在完全骨折前削弱骨骼和刺激骨骼重塑方面起着关键作用。这项研究的目的是描述压缩超负荷后皮质骨的力学性能退化的特征。采用过载-保持-再加载方案对24个纵向、低长宽比的牛皮质骨标本进行了力学测试。当过载幅度小于0.73%应变时，没有观察到超过5%的模数下降。对于每个试件，强度和泊松比的变化(P=0.02)分别比弹性模量的变化大10.8倍和266倍，这表明对于本研究中使用的试件结构，纵向弹性模量是对压缩超载最不敏感的特性之一。横向残余应变也比轴向大6.4倍(p=0.01)。这些结果表明，将微裂纹密度和形态与皮质骨压缩力学性能的变化联系起来的努力，可能受益于考虑模数降低的替代参数。
Damage accumulation plays a key role in weakening bones prior to complete fracture and in stimulating bone remodeling. The goal of this study was to characterize the degradation in the mechanical properties of cortical bone following a compressive overload. Longitudinally oriented, low-aspect ratio specimens (n = 24) of bovine cortical bone were mechanically tested using an overload-hold-reload protocol. No modulus reductions greater than 5 % were observed following overload magnitudes less than 0.73 % strain. For each specimen, changes in strength and Poisson's ratio were greater (P = 0.02) than that in modulus by 10.8- and 266-fold, respectively, indicating that, for the specimen configuration used in this study, longitudinal elastic modulus is one of the least sensitive properties to a compressive overload. Residual strains were also proportionately greater by 6.4-fold (p = 0.01) in the transverse than axial direction. These results suggest that efforts to relate microcrack density and morphology to changes in compressive mechanical properties of cortical bone may benefit from considering alternative parameters to modulus reductions.