Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging.

Pulsed illumination spectral-domain optical coherence tomography for human retinal imaging.
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DOI:
10.1364/oe.14.006739
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发表时间:
2006-07
期刊:
影响因子:
3.8
通讯作者:
J. You;Teresa Chen;M. Mujat;B. Park;J. D. de Boer
J. You;Teresa Chen;M. Mujat;B. Park;J. D. de Boer
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
J. You;Teresa Chen;M. Mujat;B. Park;J. D. de Boer

文献摘要

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我们提出了脉冲照明光谱域光学相干断层扫描(SD-OCT)在体内人类视网膜成像。分析了连续波和脉冲照明SD-OCT的信噪比,横向扫描引起的干涉条纹冲刷是导致信噪比下降的主要原因。脉冲照明可以通过在相机的积分时间期间缩短样本照明时间来减小SNR下降。首先,我们证明了SNR的好处,脉冲照明超过CW作为横向扫描速度的函数的纸张样本。最后,我们显示出更好的信噪比在视网膜图像的正常受试者与脉冲照明SD-OCT在高横向扫描速度CW。
We present pulsed illumination spectral-domain optical coherence tomography (SD-OCT) for in vivo human retinal imaging. We analyze the signal-to-noise (SNR) for continuous wave (CW) and pulsed illumination SD-OCT. The lateral beam scan motion is responsible for a SNR drop due to lateral scanning induced interference fringe washout. Pulsed illumination can reduce the SNR drop by shorter sample illumination time during the integration time of a camera. First, we demonstrate the SNR benefit of pulsed illumination over CW as function of lateral scan speed for a paper sample. Finally, we show better SNR in retinal images of a normal subject with pulsed illumination SD-OCT over CW at high lateral scanning speed.