Complete Nucleotide Sequence of KPC-3-Encoding Plasmid pKpQIL in the Epidemic Klebsiella pneumoniae Sequence Type 258

Complete Nucleotide Sequence of KPC-3-Encoding Plasmid pKpQIL in the Epidemic Klebsiella pneumoniae Sequence Type 258
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DOI:
10.1128/aac.00175-10
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发表时间:
2010-10-01
影响因子:
4.9
通讯作者:
Navon-Venezia, Shiri
Navon-Venezia, Shiri
中科院分区:
医学2区
文献类型:
--
作者:
Leavitt, Azita;Chmelnitsky, Inna;Navon-Venezia, Shiri

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我们测定了携带bla(KPC-3)的质粒pKpQIL的全DNA序列,该质粒由来自以色列的碳青霉烯耐药肺炎克雷伯菌克隆序列258 (ST 258)携带。pKpQIL是一个113,637 bp的自传质粒,属于不相容群IncFII。它由pkpn4样质粒的大骨架组成,并携带pnyc样质粒的bla(KPC-3)- Tn4401a转座子。
We have determined the entire DNA sequence of plasmid pKpQIL, the bla(KPC-3)-carrying plasmid harbored by the carbapenem-resistant Klebsiella pneumoniae clone sequence type 258 (ST 258) in Israel. pKpQIL is a 113,637-bp, self-transmissible plasmid that belongs to the incompatibility group IncFII. It consists of a large backbone of a pKPN4-like plasmid and carries the bla(KPC-3)-containing Tn4401a transposon of a pNYC-like plasmid.