Exposure to socioeconomic adversity in early life and risk of depression at 18 years: The mediating role of locus of control
Exposure to socioeconomic adversity in early life and risk of depression at 18 years: The mediating role of locus of control
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DOI：
10.1016/j.jad.2015.05.030
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发表时间：
2015-09-01
影响因子：
6.6
通讯作者：
Joinson, Carol
中科院分区：
文献类型：
--
作者：
Culpin, Iryna;Stapinski, Lexine;Joinson, Carol
背景资料：以前的研究将早期社会经济逆境与抑郁联系起来，但这种联系的机制还不清楚。控制点（LoC），一个人的控制相关的信念，已被牵连作为一个可能的机制，然而，纵向的证据来支持这是lacking.Methods：研究样本包括8803名参与者从英国队列，雅芳纵向研究的父母和孩子（ALSPAC）。早期社会经济逆境的指标收集从产前到5年，并作为一个潜在的因素建模。抑郁症是在18岁时使用临床访谈计划修订版（CIS-R）进行评估的。在16 years.Results：使用结构方程模型，我们发现，34%的总估计早期社会经济逆境和抑郁症之间的关联在18年的Nowicki-Strickland内部-外部（CNSIE）规模进行了评估，外部LoC在16年。有微弱的证据表明，从早期的社会经济逆境抑郁症的间接影响后，通过外部控制点帐户的直接途径。社会经济逆境与更多的外部LoC，这反过来，与depression.Limitations：Atabolism可能导致低估的直接和间接的影响大小在完整的案例analysis.Conclusions：结果表明，外部LoC在青春期是一个因素，调解早期逆境和抑郁症之间的联系在18岁。认知干预，寻求修改适应不良的控制信念在青春期可能是有效的，在减少抑郁症的风险后，早期生活逆境。(C)2015年，作者。由Elsevier B. V.发布。这是CC BY许可下的开放获取文章（htip：//creativecommons.urg/licenses/by/4.0/）。
Background: Previous studies have linked exposure to early socioeconomic adversity to depression, but the mechanisms of this association are not well understood. Locus of control (LoC), an individual's control-related beliefs, has been implicated as a possible mechanism, however, longitudinal evidence to support this is lacking.Methods: The study sample comprised 8803 participants from a UK cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC). Indicators of early socioeconomic adversity were collected from the antenatal period to 5 years and modelled as a latent factor. Depression was assessed using the Clinical Interview Schedule-Revised (CIS-R) at 18 years. LoC was assessed with the Nowicki-Strickland Internal-External (CNSIE) scale at 16 years.Results: Using structural equation modelling, we found that 34% of the total estimated association between early socioeconomic adversity and depression at 18 years was explained by external LoC at 16 years. There was weak evidence of a direct pathway from early socioeconomic adversity to depression after accounting for the indirect effect via external locus of control. Socioeconomic adversity was associated with more external LoC, which, in turn, was associated with depression.Limitations: Attrition may have led to an underestimation of the direct and indirect effect sizes in the complete case analysis.Conclusions: Results suggest that external LoC in adolescence is one of the factors mediating the link between early adversity and depression at 18 years. Cognitive interventions that seek to modify maladaptive control beliefs in adolescence may be effective in reducing risk of depression following early life adversity. (C) 2015 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (htip://creativecommons.urg/licenses/by/4.0/).