A Petal-type Chiral NADH Model: Design, Synthesis and its Asymmetric Reduction.
A Petal-type Chiral NADH Model: Design, Synthesis and its Asymmetric Reduction.
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花瓣型手性 NADH 模型：设计、合成及其不对称还原
DOI：
10.1038/srep17458
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发表时间：
2015-12-09
影响因子：
4.6
通讯作者：
Lan XW
中科院分区：
文献类型：
--
作者：
Bai CB;Wang NX;Wang YJ;Xing Y;Zhang W;Lan XW
用一种简便有效的方法合成了一种新型的NADH模型化合物。该模型化合物在不对称还原反应中表现出较高的反应活性和对映选择性。结果表明，手性NADH模型化合物能有效地与Mg ~（2+）形成三元配合物。当在377 nm激发时，这种新颖的C3对称NADH模型能够在460 nm处发射荧光。
A new type of NADH model compound has been synthesized by an efficient and convenient method. This model compound exhibits high reactivity and enantioselectivity in asymmetric reduction reactions. The results show that chiral NADH modelScould be effectively combined with Mg2+to form ternary complexes. This novelC3symmetrical NADH model is capable of fluorescence emission at 460 nm when excited at 377 nm.