Bone mineral density is related to blood pressure in men
Bone mineral density is related to blood pressure in men
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DOI：
10.1002/ajhb.20005
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发表时间：
2004-03
影响因子：
2.9
通讯作者：
B. Larijani;M. Bekheirnia;A. Soltani;Alireza Khalili-Far;H. Adibi;R. Jalili
中科院分区：
文献类型：
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作者：
B. Larijani;M. Bekheirnia;A. Soltani;Alireza Khalili-Far;H. Adibi;R. Jalili
本研究的目的是确定 214 名年龄 20-76 岁男性的骨矿物质密度 (BMD) 和血压之间的关系。 BMD 测量是通过双 X 射线吸收法使用 Lunar DPXMD 密度计在腰椎 (L2-L4) 和不同股骨区域进行的。使用 MPC-350 血压计测量收缩压 (SBP) 和舒张压 (DBP)。医生收集了人口统计数据，并通过食物频率调查问卷确定了参与者的膳食钙摄入量。调整年龄、体重指数、膳食钙和运动史后，多元线性回归模型显示，DBP 与股骨颈 BMD 呈负相关（β = -0.145，P = 0.032），与股骨颈 BMC 呈显着相关（β = -0.114，P = 0.079）。 SBP 与股骨颈（r = -0.171，P = 0.012）和 Ward 骨密度（r = -0.186，P = 0.006）BMD 相关，但在调整可能的混杂因素后则不然。需要进一步的研究来确定血压升高是否与低骨量的发生有因果关系。是。 J.哼。生物。 16:168–171, 2004。© 2004 Wiley-Liss, Inc.
The aim of this study was to determine the relationships between bone mineral density (BMD) and blood pressure in 214 men, age 20–76. BMD measurements were done by dual X‐ray absorptiometry using a Lunar DPXMD densitometer at the lumbar spine (L2–L4) and different femoral regions. Systolic (SBP) and diastolic (DBP) blood pressure were measured using an MPC‐350 sphygmomanometer. Physicians gathered demographic data and participants' dietary intake of calcium were determined by using food frequency questionnaires. After adjusting for age, body mass index, dietary calcium, and exercise history, multiple linear regression models showed that DBP was negatively related to femoral neck BMD (β = −0.145, P = 0.032) and just shy of significant association with femoral neck BMC (β = −0.114, P = 0.079). SBP was correlated with femoral neck (r = −0.171, P = 0.012) and Ward's (r = −0.186, P = 0.006) BMD but not after adjusting for possible confounders. Further studies are needed to determine whether elevated blood pressure is causally related to the development of low bone mass. Am. J. Hum. Biol. 16:168–171, 2004. © 2004 Wiley‐Liss, Inc.