2,3-Bisphosphoglycerate protects mitochondrial and cytosolic proteins from proteolytic inactivation.
2,3-Bisphosphoglycerate protects mitochondrial and cytosolic proteins from proteolytic inactivation.
复制标题
2,3-双磷酸甘油酸可保护线粒体和胞质蛋白免遭蛋白水解失活。
DOI:
10.1016/0006-291x(87)91468-9
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发表时间:
1987
影响因子:
3.1
通讯作者:
S. Grisolía
中科院分区:
文献类型:
--
作者:
E. Roche;E. Knecht;S. Grisolía
2,3-bisphosphoglycerate at physiological concentration similar to that found in many tissues protects effectively ornithine transcarbamoylase (OTC) from proteolytic inactivation by broken lysosomes. 2,3-bisphosphoglycerate protects also many other mitochondrial and cytosolic proteins, such as glutamate dehydrogenase (GDH) and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), from proteolysis by broken lysosomes and other proteases. It is, thus, suggested that 2,3-bisphosphoglycerate may play an important role in the control of the degradative rates of some proteins, which may explain its high concentration in certain cells.
DOI:
--
发表时间:
1984
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Hathaway,GM;Traugh,JA
通讯作者:
Traugh,JA