AutoDep:: a web-based system for deposition and validation of macromolecular structural information

AutoDep:: a web-based system for deposition and validation of macromolecular structural information
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DOI:
10.1107/s0907444900005655
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发表时间:
2000-07-01
期刊:
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
影响因子:
--
通讯作者:
Sussman, JL
Sussman, JL
中科院分区:
其他
文献类型:
--
作者:
Lin, DW;Manning, NO;Sussman, JL

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本文介绍了一个新的概念,在数据存储和验证:AutoDep(版权布鲁克海文科学协会有限责任公司)的设计和全面实施。AutoDep改变了传统的数据接受和验证主数据库的程序,使之成为一种交互式的由存放者驱动的操作,几乎消除了接受数据和公开发布数据之间的延迟。该系统充分利用了实验人员的知识和专业知识,而不是依赖于数据库管理员对结构实验及其结果进行完整和准确的描述。AutoDep由Brookhaven国家实验室(BNL)的蛋白质数据库开发,作为一个灵活和便携的系统,已经被其他主要数据库采用,并在不同的平台/操作系统上实现。AutoDep于1996年在BNL引入[参见Manning(1996),Protein Data Bank Quart.新闻快报。org/pub/pdb/doc/newsletters/bnl/newsletter96jul/newslttr.txt); Manning(1996),Protein Data Bank Quart.新闻快报。78,2(ftp://ftp.rcsb.org/pub/pdb/doc/newsletters/bnl/newsletter96oct/newslttr.txt)]。
This paper describes the design and full implementation of a new concept in data deposition and validation: AutoDep (copyright Brookhaven Science Associates LLC). AutoDep changes the traditional procedure for data acceptance and validation of the primary databases into an interactive depositor-driven operation which almost eliminates the delay between the acceptance of the data and its public release. The system takes full advantage of the knowledge and expertise of the experimenters, rather than relying on the database curators for the complete and accurate description of the structural experiment and its results. AutoDep, developed by the Protein Data Bank at Brookhaven National Laboratory (BNL) as a flexible and portable system, has already been adopted by other primary databases and implemented on different platforms/operating systems. AutoDep was introduced at BNL in 1996 [see Manning (1996), Protein Data Bank Quart. Newslett. 77, 2 (ftp://ftp.rcsb.org/pub/pdb/doc/newsletters/bnl/newsletter96jul/newslttr.txt); Manning (1996), Protein Data Bank Quart. Newslett. 78, 2 (ftp://ftp.rcsb.org/pub/pdb/doc/newsletters/bnl/newsletter96oct/newslttr.txt)].