Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.
Impact of endometriosis on quality of life and work productivity: a multicenter study across ten countries.
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DOI：
10.1016/j.fertnstert.2011.05.090
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发表时间：
2011-08
影响因子：
6.7
通讯作者：
Zondervan, Krina T.
中科院分区：
文献类型：
--
作者：
Nnoaham, Kelechi E.;Hummelshoj, Lone;Webster, Premila;d'Hooghe, Thomas;Nardone, Fiorenzo de Cicco;Nardone, Carlo de Cicco;Jenkinson, Crispin;Kennedy, Stephen H.;Zondervan, Krina T.
评估子宫内膜异位症对健康相关生活质量 (HRQoL) 和工作生产力的影响。前瞻性招募的多中心横断面研究。十个国家的十六个临床中心。共有 1,418 名年龄在 18-45 岁、之前没有手术诊断为子宫内膜异位症、接受腹腔镜检查以调查症状或接受绝育的绝经前女性。没有任何。诊断延迟、HRQoL 和工作效率。症状出现和子宫内膜异位症手术诊断之间存在 6.7 年的延迟，主要是在初级保健中，在妇女主要接受国家资助的医疗保健的中心，延迟时间更长（8.3 年与 5.5 年）。延迟与盆腔症状（慢性盆腔疼痛、痛经、性交痛和月经过多）的数量以及较高的体重指数呈正相关。与那些有类似症状且没有子宫内膜异位症的女性相比，受影响的女性的身体 HRQoL 显着降低。每位受影响的女性每周平均损失 10.8 小时（标准差 12.2），主要是由于工作效率降低。工作生产力的损失转化为每名女性每周的巨大成本，从尼日利亚的 4 美元到意大利的 456 美元。子宫内膜异位症会损害各个国家和种族的 HRQoL 和工作生产力，但女性在初级保健中仍然遇到诊断延迟的情况。需要更高的怀疑指数来加快对有症状的女性进行专家评估。未来的研究应寻求阐明与子宫内膜异位症严重程度相关的疼痛机制。
To assess the impact of endometriosis on health-related quality of life (HRQoL) and work productivity. Multicenter cross-sectional study with prospective recruitment. Sixteen clinical centers in ten countries. A total of 1,418 premenopausal women, aged 18–45 years, without a previous surgical diagnosis of endometriosis, having laparoscopy to investigate symptoms or to be sterilized. None. Diagnostic delay, HRQoL, and work productivity. There was a delay of 6.7 years, principally in primary care, between onset of symptoms and a surgical diagnosis of endometriosis, which was longer in centers where women received predominantly state-funded health care (8.3 vs. 5.5 years). Delay was positively associated with the number of pelvic symptoms (chronic pelvic pain, dysmenorrhoea, dyspareunia, and heavy periods) and a higher body mass index. Physical HRQoL was significantly reduced in affected women compared with those with similar symptoms and no endometriosis. Each affected woman lost on average 10.8 hours (SD 12.2) of work weekly, mainly owing to reduced effectiveness while working. Loss of work productivity translated into significant costs per woman/week, from US$4 in Nigeria to US$456 in Italy. Endometriosis impairs HRQoL and work productivity across countries and ethnicities, yet women continue to experience diagnostic delays in primary care. A higher index of suspicion is needed to expedite specialist assessment of symptomatic women. Future research should seek to clarify pain mechanisms in relation to endometriosis severity.
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影响因子：
9.9
作者：
Marrie, R. A.;Horwitz, R.;Vollmer, T.
通讯作者：
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影响因子：
4
作者：
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作者：
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Wright, Jeremy
DOI：
10.1016/j.jaad.2005.11.1053
发表时间：
2006-03-01
影响因子：
13.8
作者：
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通讯作者：
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影响因子：
6.3
作者：
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通讯作者：
Paice, C