Temporal Course of Cerebral Autoregulation in Patients With Narcolepsy Type 1: Two Case Reports

Temporal Course of Cerebral Autoregulation in Patients With Narcolepsy Type 1: Two Case Reports
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1 型发作性睡病患者大脑自动调节的时间过程:两个病例报告。

DOI:
10.3389/fneur.2018.01155
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发表时间:
2019-01-10
影响因子:
3.4
通讯作者:
Yang, Yi
Yang, Yi
中科院分区:
医学3区
文献类型:
--
作者:
Guo, Zhen-Ni;Sun, Xin;Yang, Yi

文献摘要

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脑自动调节是尽管动脉血压发生变化仍能维持恒定脑血流的机制。在这两个病例中,1 型发作性睡病患者的大脑自动调节功能受损,文拉法辛和氟西汀都可能具有改善受损的大脑自动调节功能的潜力。 1 型发作性睡病患者的大脑自动调节受损与神经系统症状之间可能存在关联。
Cerebral autoregulation is the mechanism by which constant cerebral blood flow is maintained despite changes in arterial blood pressure. In the two presented cases, cerebral autoregulation was impaired in patients with narcolepsy type 1, and both venlafaxine and fluoxetine may have the potential to improve the impaired cerebral autoregulation. A relationship may exist between impaired cerebral autoregulation and neurological symptoms in patients with narcolepsy type 1.