TMEM100 induces cell death in non-small cell lung cancer via the activation of autophagy and apoptosis

TMEM100 induces cell death in non-small cell lung cancer via the activation of autophagy and apoptosis
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DOI:
10.3892/or.2021.8014
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发表时间:
2021-05-01
期刊:
影响因子:
4.2
通讯作者:
He, Yujuan
He, Yujuan
中科院分区:
医学3区
文献类型:
--
作者:
He, Qian;Dong, Yilin;He, Yujuan

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肺癌是世界上最恶性的肿瘤之一。非小细胞肺癌(NSCLC)是最常见的肺癌类型,被定义为一种表现出遗传和细胞异质性的独特疾病。尽管在过去的二十年里,非小细胞肺癌的治疗取得了重大进展,但非小细胞肺癌患者的5年存活率仍然很高。
Lung cancer is one of the most malignant type of tumors worldwide. Non-small cell lung cancer (NSCLC), which is the most common type of lung cancer, is defined as a distinct disease that exhibits both genetic and cellular heterogeneity. Although in the past two decades significant advances in the treatment of NSCLC have besen performed, the 5-year survival rate of patients with NSCLC remains