Pre-pregnancy sleep duration and postpartum depression: a multicenter study in Japan
Pre-pregnancy sleep duration and postpartum depression: a multicenter study in Japan
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DOI：
10.1007/s00737-021-01136-1
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发表时间：
2021-07-13
影响因子：
4.5
通讯作者：
Kotani, Tomomi
中科院分区：
文献类型：
--
作者：
Matsuo, Seiko;Ushida, Takafumi;Kotani, Tomomi
产后抑郁症（PPD）是一个重大的公共卫生问题和世界范围内的临床优先事项.本研究旨在探讨孕前睡眠时间与产后抑郁症的关系。一项多中心回顾性研究使用了2014年至2018年期间在日本12家产科护理医院分娩的女性的临床数据。共有15，314名妇女根据其孕前睡眠时间分为五组：< 6，6-7，7-8，8-9和>= 9小时。进行单因素和多因素回归分析，以确定是否怀孕前的睡眠时间影响爱丁堡产后抑郁量表（EPDS）评分在产后1个月。我们还评估了根据孕前睡眠时间分类的经产妇和经产妇患产后抑郁症的风险是否不同。睡眠时间< 6 h和6-7 h的女性EPDS评分较高（>= 9）的校正比值比分别为2.08（95%置信区间[CI]：1.60-2.70）和1.41（95% CI：1.18-1.68），相对于睡眠时间为7-8 h的女性（作为参考组）。睡眠时间增加1小时与EPDS高评分风险降低约14%相关。睡眠时间短和EPDS评分高之间的关联在经产妇中比在经产妇中更显着。孕前睡眠时间短与EPDS评分高相关，这种关联在经产妇中比在产妇中更显着。我们的研究结果强调了收集孕前睡眠时间信息的重要性，以识别PPD高风险女性。
Postpartum depression (PPD) is as a major public health issue and clinical priority worldwide. This study aimed to investigate the association between pre-pregnancy sleep duration and PPD. A multicenter retrospective study was conducted using clinical data of women who delivered at term between 2014 and 2018 at 12 maternity care hospitals in Japan. A total of 15,314 women were stratified into five groups according to their pre-pregnancy sleep duration: < 6, 6-7, 7-8, 8-9, and >= 9 h. Univariate and multivariate regression analyses were conducted to determine whether pre-pregnancy sleep duration affects the Edinburgh Postnatal Depression Scale (EPDS) scores at 1 month postpartum. We also evaluated whether the risk for PPD differs between primipara and multipara women classified according to pre-pregnancy sleep duration. The adjusted odds ratio for high EPDS scores (>= 9) among women who slept for < 6 h and 6-7 h was 2.08 (95% confidence interval [CI]: 1.60-2.70) and 1.41 (95% CI: 1.18-1.68), respectively, relative to that in women with 7-8 h of sleep as the reference group. A 1-h increase in sleep duration was associated with an approximately 14% reduction in the risk for high EPDS scores. The association between short sleep duration and high EPDS scores was more remarkable in multipara women than in primipara women. Short pre-pregnancy sleep duration is associated with high EPDS scores, and this association is more significant in multipara women than in primipara women. Our findings emphasize the importance of collecting information on pre-pregnancy sleep duration to identify women at a high risk for PPD.