Brain Metastasis From Prostate Adenocarcinoma: Case Report and Review of Literature
Brain Metastasis From Prostate Adenocarcinoma: Case Report and Review of Literature
复制标题
前列腺腺癌脑转移：病例报告及文献复习
作者：
G. Taddei;S. Marzi;G. Coletti;D. De Paulis;A. Ricci;R. Galzio
前列腺癌转移到中枢神经系统是罕见的。它通常代表一年内死亡的终末期事件，通常是由于晚期全身性疾病。我们从一个病例报告开始，回顾了相关文献，从流行病学到临床表现和治疗策略，重点讨论了这种罕见的实体。本文报告1例多发性脑前列腺转移，并对相关文献进行复习。治疗颅内转移的方法包括神经外科手术、外部放射治疗和激素调节。手术联合全脑放射治疗在控制脑病变方面似乎是有效的，既减轻了神经系统症状，又延长了生存期，即使预后仍然很差。从这个病例中，我们得出结论，前列腺癌脑转移是一种罕见的终末期事件，经常因晚期全身性疾病而在一年内死亡。更好地了解前列腺癌的生物学将有助于阐明其转移到大脑的基础。
It is rare for prostate carcinoma to metastasize to the central nervous system. It often represents a terminal event with death in one year frequently due to the advanced systemic disease. Starting by a case report, we also reviewed the relevant literature to focus on this uncommon entity from epidemiology to clinical manifestation and therapeutic strategies. In this article, a case of multiple brain prostate metastasis is reported and a review of relevant literature is also discussed. Treatments available for intracranial metastasis include neurosurgery, external beam radiation and hormonal manipulation. Surgery associated with whole brain radiotherapy seems to be effective in the control of brain lesions both relieving neurological symptoms and prolonging survival, even if prognosis remains dismal. From this case, we concluded that brain metastasis from prostate carcinoma is a rare, terminal event with death in one year frequently due to the advanced systemic disease. A better understanding of the biology of prostate carcinoma will help clarify the basis for its metastasis to the brain.
脑肿瘤儿童的诊断、组织学特征和生存率与年龄相关的变化：1930-1979 年。
影响因子：
4.8
作者：
Gilles,FH;Sobel,EL;Tavaré,CJ;Leviton,A;Hedley-Whyte,ET
通讯作者：
Hedley-Whyte,ET