Thieme Chemistry Journal Awardees - Where are They Now? Efforts towards the Total Synthesis of Vinigrol
Thieme Chemistry Journal Awardees - Where are They Now? Efforts towards the Total Synthesis of Vinigrol
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DOI：
10.1055/s-0028-1087378
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发表时间：
2009-01-02
期刊：
影响因子：
2
通讯作者：
Njardarson, Jon T.
中科院分区：
文献类型：
--
作者：
Morton, Jason G. M.;Kwon, Laura D.;Njardarson, Jon T.
详细介绍了醋氨醇全合成的两个关键步骤-氧化脱芳化和分子内diet - alder环加成-提供顺式十氢化萘核心。本文还描述了一种新的、温和的合成对醌类化合物的方法。
A strategy for the total synthesis of vinigrol is detailed with two key steps - oxidative dearomatization and intramolecular Diets-Alder cycloaddition - providing the cis-decalin core. A novel and mild means for the formation of ortho-quinone methides is also described.