Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19
Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19
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DOI：
10.1007/s11095-020-02842-8
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发表时间：
2020-05-25
影响因子：
3.7
通讯作者：
Ekins, Sean
中科院分区：
文献类型：
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作者：
Baker, Nancy;Williams, Antony J.;Ekins, Sean
COVID-19疫情凸显了药物再利用的重要作用。季铵化合物，如氯化铵，十六烷基吡啶和miramistin代表广泛使用的抗菌分子，具有众所周知的广谱抗病毒活性，并代表了一个重新利用的机会，作为治疗SARS-CoV-2。
The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing opportunity as therapeutics against SARS-CoV-2.