IgA nephropathy in children and adults: comparison of histologic features and clinical outcomes
IgA nephropathy in children and adults: comparison of histologic features and clinical outcomes
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DOI：
10.1093/ndt/gfn014
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发表时间：
2008-08-01
影响因子：
6.1
通讯作者：
Bartosh, Sharon M.
中科院分区：
文献类型：
--
作者：
Haas, Mark;Rahman, M. Hafizur;Bartosh, Sharon M.
背景虽然一些研究报告伊加肾病在儿童中具有相对良性的临床病程，但其他研究表明，伊加肾病儿科患者随访至成年期的肾脏结局与诊断为成人的患者相似。这种变异性可能与诊断为儿童与成人的患者队列的组织学严重程度差异有关。我们回顾性研究了99名儿童和青少年的肾活检结果、临床表现和肾存活率之间的相关性，
Background. While some studies have reported that IgA nephropathy has a relatively benign clinical course in children, others have shown that renal outcomes of paediatric patients with IgA nephropathy followed into adulthood are similar to those of patients diagnosed as adults. Some of this variability may be related to differences in histologic severity of cohorts of patients diagnosed as children versus adults.Methods. We retrospectively examined correlations between renal biopsy findings, clinical features at presentation and renal survival in 99 children and adolescents (