Antimicrobial effectiveness of a highly concentrated chlorhexidine varnish treatment in teenagers with fixed orthodontic appliances
Antimicrobial effectiveness of a highly concentrated chlorhexidine varnish treatment in teenagers with fixed orthodontic appliances
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DOI：
10.2319/070605-218
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发表时间：
2006-11-01
影响因子：
3.4
通讯作者：
Attin, Thomas
中科院分区：
文献类型：
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作者：
Attin, Rengin;Ilse, Anika;Attin, Thomas
目的：评估变形链球菌（MS）的密集定植的牙齿与固定正畸器具治疗后，高浓度（36%）洗必泰varnish.Materials和方法：健康受试者（n = 19）与固定正畸器具和高细菌MS计数唾液中招募。为了建立基线登记，对托槽附近的牙菌斑进行取样并在Dentocult（R）条上培养。在专业牙齿清洁之后，将洗必泰清漆施加在所有牙齿上8分钟。在托槽周围牙菌斑涂抹清漆2周后，评估ms的牙菌斑化程度。对于统计分析，数据进行了重复测量design.Results：2周后，ms计数减少相比，基线值。然而，只有微弱的减少达到统计学意义（P = 0.049）。结论：高浓度的洗必泰清漆在固定正畸矫治器的患者中的应用不会导致治疗后2周MS数量的明显减少。
Objective: To evaluate the recolonization pattern of Mutans streptococci (ms) on densely colonized teeth with fixed orthodontic appliances after treatment with a highly concentrated (36%) chlorhexidine varnish.Materials and Methods: Healthy subjects (n = 19) with fixed orthodontic appliances and high bacterial ms counts in saliva were recruited. In order to establish a baseline registration, plaque adjacent to brackets was sampled and cultivated on Dentocult(R) strips. Following professional tooth cleaning, chlorhexidine varnish was applied on all teeth for 8 minutes. The degree of recolonization with ms was assessed 2 weeks after varnish application in plaque around the brackets. For statistical analysis, the data were subjected to a repeated measures design.Results: After 2 weeks, ms counts were reduced as compared to baseline values. However, the reduction only weakly met statistical significance (P =.049).Conclusions: The application of a highly concentrated chlorhexidine varnish in patients with fixed orthodontic appliances does not result in a distinct reduction of ms numbers 2 weeks after treatment.