Fabrication and characterization of microelectromechanical systems-based gas chromatography column with embedded micro-posts for separation of environmental carcinogens.
Fabrication and characterization of microelectromechanical systems-based gas chromatography column with embedded micro-posts for separation of environmental carcinogens.
复制标题
DOI：
10.1016/j.chroma.2013.03.022
复制
发表时间：
2013-05
期刊：
影响因子：
--
通讯作者：
Jianhai Sun;D. Cui;Xing Chen;Lulu Zhang;H. Cai;Hui Li
中科院分区：
文献类型：
--
作者：
Jianhai Sun;D. Cui;Xing Chen;Lulu Zhang;H. Cai;Hui Li
为了增加柱的总表面积，使其能够承载更多的固定相，减小柱的有效宽度，从而提高分离效率，本文研制了一种嵌入微柱的微型气相色谱柱。建议的柱具有更高的样品容量，因为总表面积比具有相同尺寸的开放柱大约3倍。通过数值模拟优化了直线通道中微柱的位置和弯曲通道中微柱的结构，以使通道中的流速均匀。结果表明，该色谱柱分离5种环境致癌物的时间小于50 s，分离效率约为9500板/m，洗脱出高度对称的高斯峰。
In this paper, a micro gas chromatography (μGC) column with embedded micro-posts was developed for increasing overall surface area of the columns which is able to support more of the stationary phase and reducing the effective width of the column, leading to higher separation efficiency. The proposed columns have a higher sample capacity as the overall surface area is about 3 times larger than that of open columns with the same dimensions. In order to achieve an even flow velocity in the channels, the location of the micro-posts in the linear channels and the configuration of curved channels were optimized by numerical simulation. The results have indicated that the proposed column separated 5 environmental carcinogens in less than 50s, achieved a separation efficiency of about 9500plates/m and eluted highly symmetrical Gaussian peaks.