Late respiratory outcomes after preterm birth
Late respiratory outcomes after preterm birth
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DOI：
10.1016/j.earlhumdev.2007.09.006
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发表时间：
2007-12-01
影响因子：
2.5
通讯作者：
Greenough, Anne
中科院分区：
文献类型：
--
作者：
Greenough, Anne
慢性呼吸道疾病在早产后很常见，特别是如果并发支气管肺发育不良（BPD）的话。受影响的患者可以保持氧气依赖长达数月，但通常超过两年。那些需要在家里补充氧气的人增加了医疗保健的使用，即使在学龄前，不再依赖氧气。超过50%的“BPD”患者在头两年需要再次入院，特别是呼吸道感染。早产儿，特别是那些患有BPD的儿童，在学龄期和青春期比足月出生的对照组更容易遭受频繁的麻烦症状。这与气道阻塞的证据有关。虽然肺功能随着临床状况的改善而改善，但即使在患有严重BPD的年轻人中也可以检测到异常。目前，严重的BPD并不常见，但那些“新”BPD可能有异常的产前肺生长，他们是否达到适当的追赶肺生长需要仔细调查。(c)2007爱思唯尔爱尔兰有限公司保留所有权利。
Chronic respiratory morbidity is common following premature birth, particularly if complicated by bronchopulmonary dysplasia (BPD) development. Affected patients can remain oxygen dependent for many months, but unusually beyond two years. Those requiring supplementary oxygen at home have increased healthcare utilisation, even during the preschool years when no longer oxygen dependent. More than 50% of "BPD" patients require readmission in the first two years, particularly for respiratory infections. Prematurely born children, especially those who had BPD, are more likely to suffer frequent troublesome symptoms at school age and in adolescence than term born controls. This is associated with evidence of airways obstruction. Although lung function improves as the clinical condition improves, abnormalities can be detected even in young adults who had severe BPD. Nowadays, severe BPD is uncommon, but those with "new" BPD may have abnormal antenatal lung growth, whether they achieve appropriate catch up lung growth needs careful investigation. (c) 2007 Elsevier Ireland Ltd. All rights reserved.