Synaptic transmission in the retina.

Synaptic transmission in the retina.
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DOI:
10.1016/0959-4388(91)90087-n
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发表时间:
1991-08-01
影响因子:
5.7
通讯作者:
Copenhagen, D R
Copenhagen, D R
中科院分区:
医学2区
文献类型:
--
作者:
Copenhagen, D R

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视网膜研究中最近的一个亮点是发表了证据,证明ON双极细胞的反应是由cGMP介导的第二信使系统产生的。这种GTP结合蛋白机制通过谷氨酸(感光神经递质)与2-氨基-4-膦酰基丁酸(APB)类受体的结合而激活。
A recent highlight in the study of the retina has been the publication of evidence that the response of the ON bipolar cells is generated by a cGMP-mediated second messenger system. This GTP-binding protein mechanism is activated by the binding of glutamate, the photoreceptor neurotransmitter, to the 2-amino-4-phosphonobutyrate (APB) class of receptor.