EFFECT OF SPINAL AND SKIN TEMPERATURES ON FIRING RATE AND THERMOSENSITIVITY OF PREOPTIC NEURONS
EFFECT OF SPINAL AND SKIN TEMPERATURES ON FIRING RATE AND THERMOSENSITIVITY OF PREOPTIC NEURONS
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DOI：
10.1113/jphysiol.1974.sp010627
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发表时间：
1974-01-01
影响因子：
5.5
通讯作者：
HARDY, JD
中科院分区：
文献类型：
--
作者：
BOULANT, JA;HARDY, JD
1.在麻醉兔，视前单个单位的活动记录，而视前，脊髓和皮肤温度被独立操纵。2.对视前温度不敏感的单位的特征是低放电率，也是由一个非常低的发病率下丘脑外热敏性。3. 37个单位具有积极的系数，视前温度进行了测试，其响应脊髓或皮肤温度。其中，22个单位对下丘脑外温度做出反应，其中17个单位具有正热系数。此外，下丘脑外热敏感性的发病率普遍增加之间的较高的发射单位。4. 22个单位有负系数的视前温度，并测试其下丘脑温度敏感性。其中，16个单位有双重热敏性，10个下丘脑外温度的负系数。此外，下丘脑外温度敏感性的发生率与放电频率水平之间没有相关性。5.在单位具有积极的系数为preoptic温度，增加射击率，由于下丘脑外温度，一般会导致减少preoptic热敏性。相反，降低的放电率通常导致增加的视前热敏性。6.在单位具有负系数的视前温度，增加放电率，由于下丘脑外温度，通常增加视前温度敏感性，而放电率下降往往会降低视前温度的敏感性。
1. In anaesthetized rabbits, preoptic single unit activity was recorded while preoptic, spinal cord and skin temperatures were independently manipulated. 2. The units that were insensitive to preoptic temperature were characterized by low firing rates and also by a very low incidence of extrahypothalamic thermosensitivity. 3. Thirty-seven units having positive coefficients to preoptic temperature were tested for their response to spinal or skin temperature. Of these, twenty-two units responded to extrahypothalamic temperature, seventeen with positive thermal coefficients. In addition, the incidence of extrahypothalamic thermosensitivity generally increased among the higher firing units. 4. Twenty-two units had negative coefficients for preoptic temperature and were tested for their extrahypothalamic thermosensitivities. Of these, sixteen units had dual thermosensitivities, ten with negative coefficients for the extrahypothalamic temperatures. In addition, there was no correlation between the incidence of extrahypothalamic thermosensitivity and the level of firing rate. 5. In the units having positive coefficients for preoptic temperature, an increased firing rate, due to extrahypothalamic temperature, generally resulted in a decreased preoptic thermosensitivity. Conversely, a decreased firing rate usually resulted in an increased preoptic thermosensitivity. 6. In the units having negative coefficients for preoptic temperature, an increased firing rate, due to extrahypothalamic temperature, usually increased the preoptic thermosensitivity; while a decreased firing rate tended to decrease the sensitivity to preoptic temperature.