Coping Behaviors and Incident Kidney Disease.
Coping Behaviors and Incident Kidney Disease.
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DOI：
10.34067/kid.0000000000000179
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发表时间：
2023-08-01
期刊：
影响因子：
--
通讯作者：
Crews DC
中科院分区：
文献类型：
--
作者：
Novick TK;Custer J;Zonderman AB;Evans MK;Hladek M;Kuczmarski M;Rathouz PJ;Crews DC
适应性应对行为与较低的CKD发病率相关。应对行为可能是预防CKD的一个目标。一个人如何应对可能会改变他们的肾功能的轨迹。我们的目的是评估应对行为是否与CKD事件或肾功能快速下降有关。我们使用的数据来自健康老龄化在社区的多样性在整个寿命研究（巴尔的摩，MD）的纵向分析。在第1次访视时使用简明科普量表测量适应性和适应不良应对行为结构。我们使用多元logistic回归评估应对量表中每增加一分，发生CKD和肾功能快速下降的几率，并根据基线人口统计学和临床变量进行调整。在1935名参与者中，平均年龄为48岁，44%为男性，56%为黑人，基线平均（SD）eGFR为91（16）ml/min/1.73 m2。在平均8.2年后，113名参与者发生了CKD事件，341名参与者发生了肾功能快速下降。与那些报告他们通常根本不使用适应性应对行为（如情感支持）的人相比，那些最常使用适应性应对的人发生CKD的几率较低。适应性应对每增加1个单位，对应于CKD事件的调整后比值降低2%（比值比，0.98; 95%置信区间，0.95 - 0.99）。适应不良应对行为与CKD事件之间无相关性。应对行为与肾功能快速下降无关。适应性应对行为与较低的CKD发病率相关，可以作为促进CKD预防的目标。医疗保健在这种联系中的作用是一个值得进一步研究的领域。
Adaptive coping behaviors are associated with lower odds of incident CKD. Coping behaviors could represent a target to prevent CKD. How someone copes may alter the trajectory of their kidney function. We aimed to evaluate whether coping behaviors were associated with incident CKD or rapid kidney function decline. We used data from the Healthy Aging in Neighborhoods of Diversity across the Life Span study (Baltimore, MD) for this longitudinal analysis. Adaptive and maladaptive coping behavioral constructs were measured using the Brief COPE Inventory at visit 1. We used multiple logistic regression to assess the odds of incident CKD and rapid kidney function decline per point increase in coping scales and adjusted for baseline demographics and clinical variables. Of 1935 participants, mean age was 48 years, 44% were male, 56% were Black persons, and baseline mean (SD) eGFR was 91 (16) ml/min per 1.73 m2. After a median of 8.2 years, 113 participants developed incident CKD and 341 had rapid kidney function decline. Compared with those who reported they usually did not use adaptive coping behaviors at all (such as emotional support), those with the highest use of adaptive coping had lower odds of incident CKD. Every 1-unit increase in adaptive coping corresponded with a 2% lower adjusted odds of incident CKD (odds ratio, 0.98; 95% confidence interval, 0.95 to 0.99). There was no association between maladaptive coping behaviors and incident CKD. Coping behaviors were not associated with rapid kidney function decline. Adaptive coping behaviors were associated with lower odds of incident CKD and could represent a target to facilitate CKD prevention. The role of medical care in this association is an area worthy of further investigation.
影响因子：
2.7
作者：
Hapunda, Given
通讯作者：
Hapunda, Given
影响因子：
3.8
作者：
Boima, Vincent;Yorke, Ernest;Ganu, Vincent;Gyaban-Mensah, Anna;Ekem-Ferguson, George;Kretchy, Irene Akwo;Mate-Kole, Charles Christopher
通讯作者：
Mate-Kole, Charles Christopher