EXPORT WITHOUT PROTEOLYTIC PROCESSING OF INNER AND OUTER-MEMBRANE PROTEINS ENCODED BY F-SEX FACTOR TRA CISTRONS IN ESCHERICHIA-COLI MINICELLS
EXPORT WITHOUT PROTEOLYTIC PROCESSING OF INNER AND OUTER-MEMBRANE PROTEINS ENCODED BY F-SEX FACTOR TRA CISTRONS IN ESCHERICHIA-COLI MINICELLS
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DOI：
10.1073/pnas.76.10.4837
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发表时间：
1979-01-01
影响因子：
11.1
通讯作者：
HERRLICH, P
中科院分区：
文献类型：
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作者：
ACHTMAN, M;MANNING, PA;HERRLICH, P
大多数由大肠杆菌 F 性因子编码的 tra 蛋白都整合到小细胞包膜中。 tra蛋白被分配至细胞质（TraIp和2b）、内膜（TraEp、TraMp和TraSp）和外膜（6e、TraAp、TraBp、TraJp、TraKp、TraLp和TraTp）。 TraDp 和 6d 两种蛋白与内膜和外膜相关。输出到内膜或外膜的蛋白质没有经历蛋白水解切割（加工），而β-内酰胺酶则被正常加工。
Most tra proteins encoded by the E. coli F sex factor are incorporated into the minicell envelope. The tra proteins were assigned to cytoplasm (TraIp and 2b), inner membrane (TraEp, TraMp and TraSp), and outer membrane (6e, TraAp, TraBp, TraJp, TraKp, TraLp and TraTp). Two proteins, TraDp and 6d, were associated with both inner and outer membranes. The proteins exported to the inner or outer membranes did not undergo proteolytic cleavage (processing) whereas .beta.-lactamase was processed normally.