Total resection combined with osteotomy is more effective for orbital solitary fibrous tumor excision: a report of three cases
Total resection combined with osteotomy is more effective for orbital solitary fibrous tumor excision: a report of three cases
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DOI：
10.1007/s10792-016-0421-2
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发表时间：
2018-02-01
影响因子：
1.6
通讯作者：
Hirano, Akiyoshi
中科院分区：
文献类型：
--
作者：
Tanaka, Katsuya;Yano, Hiroki;Hirano, Akiyoshi
孤立性纤维性肿瘤是一种通常发生于胸膜和间皮表面的肿瘤。本文报告三例罕见的眼眶孤立性纤维瘤，并讨论其诊断及治疗。所有三个病例均接受手术切除，并显示满意的美学和功能结果。对于明确的诊断，免疫组化染色的蛋白质，如波形蛋白，CD 34和bcl-2和苏木精和伊红（H&E）染色，以确定梭形细胞肿瘤的形态特征与部分storiform模式和鹿角形血管是必不可少的。眼眶孤立性纤维瘤的治疗原则是完全切除，因为预后取决于控制肿瘤进展，这可能难以单独使用化疗和放疗。
A solitary fibrous tumor is a neoplasm generally arising from the mesothelial surfaces of the pleura and mesothelium. In this paper, we describe three cases of rare solitary fibrous tumors arising from the orbit and discuss the management of the tumors, including diagnosis and treatment. All three cases were treated by surgical resection and showed satisfactory aesthetic and functional results. For a definitive diagnosis, immunohistochemical staining for proteins such as vimentin, CD34 and bcl-2 and hematoxylin and eosin (H&E) staining for identifying the morphological characteristics of spindle cell tumors with a partially storiform pattern and staghorn vessels are indispensable. The principle of treatment for orbital solitary fibrous tumor is complete resection because the prognosis depends on controlling tumor progression, which can be difficult with chemotherapy and radiotherapy alone.