ABO BLOOD-GROUP, SECRETOR STATE, AND SUSCEPTIBILITY TO RECURRENT URINARY-TRACT INFECTION IN WOMEN

ABO BLOOD-GROUP, SECRETOR STATE, AND SUSCEPTIBILITY TO RECURRENT URINARY-TRACT INFECTION IN WOMEN
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DOI:
10.1136/bmj.285.6334.7
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发表时间:
1982-01-01
影响因子:
105.7
通讯作者:
ELTON, RA
ELTON, RA
中科院分区:
医学1区
文献类型:
--
作者:
KINANE, DF;BLACKWELL, CC;ELTON, RA

文献摘要

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对319例反复尿路感染妇女进行ABO血型和分泌状态测定,并与334例年龄相仿的对照组进行比较。与其他类型相比,不分泌血型物质的B和AB血型女性显示复发性尿路感染的显著相对风险为3.12(95%置信限,1.49和6.52)。这似乎是一个真正的协同作用的例子,其中缺乏抗B同种血凝素和分泌物质相结合,使复发性尿路感染的风险增加。血型和分泌状态的确定可以提供额外的信息,以确定那些处于危险之中。
ABO blood group and secretor state was determined in 319 women with recurrent urinary tract infection and compared with those of a control group of 334 women of similar age ranges. Women of blood groups B and AB who are non-secretors of blood group substances showed a significant relative risk of recurrent urinary tract infection of 3.12 (95% confidence limits, 1.49 and 6.52) in comparison with other types. This appears to be a genuine example of synergy in which absence of anti-B isohemagglutinin and secretor substances combines to give an incresed risk of recurrent urinary tract infection. Determination of blood group and secretor state may provide additional information in identifying those at risk.