Delivery cost of human papillomavirus vaccination of young adolescent girls in Peru, Uganda and Viet Nam
Delivery cost of human papillomavirus vaccination of young adolescent girls in Peru, Uganda and Viet Nam
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DOI：
10.2471/blt.12.113837
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发表时间：
2013-08-01
影响因子：
11.1
通讯作者：
LaMontagne, D. Scott
中科院分区：
文献类型：
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作者：
Levin, Carol E.;Hoang Van Minh;LaMontagne, D. Scott
目的评估秘鲁、乌干达和越南青少年少女接种人乳头瘤病毒（HPV）疫苗的增量成本。方法从参与5个HPV疫苗接种示范项目的机构样本中收集数据：秘鲁、乌干达和越南采用学校为基础的接种，越南也采用卫生中心为基础的接种;乌干达也采用了包括现有保健服务在内的综合提供办法。采用微成本计算方法指导关于资源（即工作人员、用品和设备）使用情况的数据收集，数据来自政府、示范项目和保健中心的行政记录。交付费用以2009年美元表示。完全与项目有关的费用和疫苗的成本excluded.Findings经济交付成本每剂疫苗的范围从1. 44美元的综合推广在乌干达的3. 88美元，以学校为基础的交付在秘鲁。在越南，每剂疫苗的最低成本是在保健中心提供的1.92美元。费用概况显示，一般而言，最大的促成因素是项目开办费用和经常性人事费。结论秘鲁、乌干达和越南的少女接种HPV疫苗的费用高于目前计划免疫的疫苗费用，将接种纳入现有卫生服务体系后，每剂疫苗的费用较低。
Objective To estimate the incremental delivery cost of human papillomavirus (HPV) vaccination of young adolescent girls in Peru, Uganda and Viet Nam.Methods Data were collected from a sample of facilities that participated in five demonstration projects for HPV vaccine delivery: school-based delivery was used in Peru, Uganda and Viet Nam; health-centre-based delivery was also used in Viet Nam; and integrated delivery, which involved existing health services, was also used in Uganda. Microcosting methods were used to guide data collection on the use of resources (i.e. staff, supplies and equipment) and data were obtained from government, demonstration project and health centre administrative records. Delivery costs were expressed in 2009 United States dollars (US$). Exclusively project-related expenses and the cost of the vaccine were excluded.Findings The economic delivery cost per vaccine dose ranged from US$ 1.44 for integrated outreach in Uganda to US$ 3.88 for school-based delivery in Peru. In Viet Nam, the lowest cost per dose was US$ 1.92 for health-centre-based delivery. Cost profiles revealed that, in general, the largest contributing factors were project start-up costs and recurrent personnel costs. The delivery cost of HPV vaccine was higher than published costs for traditional vaccines recommended by the Expanded Programme on Immunization (EPI).Conclusion The cost of delivering HPV vaccine to young adolescent girls in Peru, Uganda and Viet Nam was higher than that for vaccines currently in the EPI schedule, The cost per vaccine dose was lower when delivery was integrated into existing health services.