MITOTIC DIVISION IN PANCREATIC BETA CELLS

MITOTIC DIVISION IN PANCREATIC BETA CELLS
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DOI:
10.1126/science.163.3870.941
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发表时间:
1969-01-01
期刊:
影响因子:
56.9
通讯作者:
CHICK, WL
CHICK, WL
中科院分区:
综合性期刊1区
文献类型:
--
作者:
LIKE, AA;CHICK, WL

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在没有前体细胞群体的情况下,经过一段时间的饮食限制后,遗传性糖尿病小鼠(C57Bl/Ks-DBdb)的胰岛细胞团成功扩张。合成胰岛素的分化细胞保留了进行有丝分裂的能力。
Successful expansion of the islet cell mass occurs in genetically diabetic mice (C57 Bl/Ks-dbdb) following a period of dietary restriction, in the absence of a population of precursor cells. Differentiated cells that synthesize insulin retain the capability of undergoing mitotic division.