Nineteen-Year Trends in Risk Factors, Clinical Characteristics and Prognosis in Lacunar Infarcts
Nineteen-Year Trends in Risk Factors, Clinical Characteristics and Prognosis in Lacunar Infarcts
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腔隙性梗塞危险因素、临床特征和预后的十九年趋势
DOI：
10.1159/000319460
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发表时间：
2010
影响因子：
5.7
通讯作者：
M. Oliveres
中科院分区：
文献类型：
--
作者：
A. Arboix;J. Massons;L. García;C. Targa;E. Comes;O. Parra;M. Oliveres
背景：使用巴塞罗那 Sagrat Cor 医院卒中登记处对 1986 年至 2004 年首次脑腔隙性梗塞的心血管危险因素、临床特征和早期结果进行了评估，并与非腔隙性梗塞患者的数据进行了比较。方法：研究人群包括 566 名腔隙性梗塞患者和 1,516 名非腔隙性梗塞患者。对 1986-1992 年、1993-1998 年和 1999-2004 年期间的长期趋势进行了分析。结果：整个时间段内，年龄和高龄患者（≥85 岁）的百分比显着增加（p < 0.001）。高血压患者比例显着下降，但慢性阻塞性肺疾病患者比例上升。脑部磁共振成像（MRI）的使用也显着增加。中位住院时间显着缩短。结论：19 年期间的显着变化包括患者年龄、高龄患者（≥ 85 岁）频率和 MRI 研究使用的增加，而高血压频率和住院时间减少。
Background: Cardiovascular risk factors, clinical features and early outcome of first-ever cerebral lacunar infarcts from 1986 to 2004, using the Sagrat Cor Hospital of Barcelona Stroke Registry, were assessed and compared with data from patients with nonlacunar infarction. Methods: The study population consisted of 566 patients with lacunar infarct and 1,516 patients with nonlacunar infarct. Secular trends for the periods 1986–1992, 1993–1998 and 1999–2004 were analyzed. Results: Age and the percentage of very old patients (≧85 years old) increased significantly (p < 0.001) throughout the time period. There was a significant decrease in the percentage of patients with hypertension, but the percentage of patients with chronic obstructive pulmonary disease increased. The use of brain magnetic resonance imaging (MRI) also increased significantly. The median length of hospital stay decreased significantly. Conclusions: Significant changes over a 19-year period included an increase in the patients’ age, frequency of very old patients (≧85 years old) and use of MRI studies, whereas the frequency of hypertension and length of hospital stay decreased.