SOME ELECTRICAL PROPERTIES OF A NUCLEAR MEMBRANE EXAMINED WITH A MICROELECTRODE.
SOME ELECTRICAL PROPERTIES OF A NUCLEAR MEMBRANE EXAMINED WITH A MICROELECTRODE.
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DOI：
10.1085/jgp.46.6.1123
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发表时间：
1963-07
期刊：
影响因子：
--
通讯作者：
KANNO Y
中科院分区：
文献类型：
--
作者：
LOEWENSTEIN WR;KANNO Y
用微电极对黄背果蝇腺细胞核进行了原位和离体的电位和电阻测量。核质边界被认为是相当不渗透的离子扩散。它提出了一个电阻的顺序为1 × cm 2，并维持一个“休息”的潜力，核质是约15毫伏负相对于细胞质。电阻和电势似乎都与核膜有关：当核膜被实验性地穿孔时，电势下降到零，电阻下降到其原始值的一小部分。
Electrical potential and resistance were measured with microelectrodes in in situ and isolated nuclei of gland cells of Drosophila flavorepleta. The nucleus-cytoplasm boundary was found to be rather impermeable to ion diffusion. It presents a resistance of the order of 1 Ω cm2 and sustains a "resting" potential, the nucleoplasm being about 15 mv negative with respect to the cytoplasm. Both the resistance and potential appear to be associated with the nuclear membrane: the potential declines to zero and the resistance to a fraction of its original value, when the membrane is perforated experimentally.