A magnetic resonance imaging framework for quantifying intervertebral disc deformation in vivo: Reliability and application to diurnal variations in lumbar disc shape
A magnetic resonance imaging framework for quantifying intervertebral disc deformation in vivo: Reliability and application to diurnal variations in lumbar disc shape
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DOI：
10.1016/j.jbiomech.2018.01.045
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发表时间：
2018-04-11
影响因子：
2.4
通讯作者：
DeFrate, Louis E.
中科院分区：
文献类型：
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作者：
Martin, John T.;Oldweiler, Alexander B.;DeFrate, Louis E.
在美国，下腰痛是一种重要的社会经济负担，腰椎间盘退变经常被认为是原因之一。间盘在脊柱中起着重要的机械作用，但间盘功能和背痛之间的关系尚不清楚。这项工作的目的是开发一种使用磁共振成像(MRI)和三维建模来测量活体椎间盘变形的技术。使用这种方法，我们发现盘的几何形状是可以测量的，其精度小于体素的平面内尺寸(大约100微米，是MRI像素大小的10%)。此外，对于单个评价者的多个试验，在平均椎间盘高度、椎间盘周长、椎间盘体积和区域椎间盘高度测量之间有很好的一致性(标准差
Low back pain is a significant socioeconomic burden in the United States and lumbar intervertebral disc degeneration is frequently implicated as a cause. The discs play an important mechanical role in the spine, yet the relationship between disc function and back pain is poorly defined. The objective of this work was to develop a technique using magnetic resonance imaging (MRI) and three-dimensional modeling to measure in vivo disc deformations. Using this method, we found that disc geometry was measurable with precision less than the in-plane dimensions of a voxel (approximate to 100 mu m, 10% of the MRI pixel size). Furthermore, there was excellent agreement between mean disc height, disc perimeter, disc volume and regional disc height measurements for multiple trials from an individual rater (standard deviation