Preparation and characterization of copper nanoparticles/zinc oxide composite modified electrode and its application to glucose sensing
Preparation and characterization of copper nanoparticles/zinc oxide composite modified electrode and its application to glucose sensing
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DOI：
10.1016/j.msec.2009.09.001
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发表时间：
2010-01-01
影响因子：
7.9
通讯作者：
Wang, Sea-Fue
中科院分区：
文献类型：
--
作者：
Kumar, S. Ashok;Cheng, Hui-Wen;Wang, Sea-Fue
我们报道了一种使用铜纳米粒子（Cu-NPs）附着氧化锌（ZnO）薄膜涂层电极选择性检测D(+)-葡萄糖的新方法。将ZnO和Cu-NPs逐层电化学沉积在氧化铟锡（ITO）镀膜玻璃电极和玻碳电极上。通过扫描电镜（SEM）和原子力显微镜（AFM）表征了Cu-NPs/ZnO复合膜的形貌。分别。SEM和AFM证实了电极表面存在纳米尺寸的Cu-NPs/ZnO复合颗粒。此外，x射线衍射图显示，Cu-NPs和ZnO薄膜附着在电极表面。事实上，Cu-NPs/ZnO复合修饰电极在碱性（0.1 M NaOH）溶液中表现出优异的葡萄糖氧化电催化活性。此外，我们利用Cu-NPs/ZnO复合修饰电极作为葡萄糖检测的电化学传感器。该葡萄糖传感器在1 × 10(-6) M ~ 1.53 × 10(-3) M范围内呈线性关系，检测限（S/N = 3）为2 × 10(-7) M。Cu-NPs/ZnO复合材料作为一种非酶促葡萄糖传感器具有灵敏度高、稳定性好、重复性好、选择性好、响应速度快等特点。该方法适用于人体尿液中葡萄糖的测定，结果令人满意。(C) 2009 Elsevier B.V.版权所有
We report a new method for selective detection of D(+)-glucose using a copper nanoparticles (Cu-NPs) attached zinc oxide (ZnO) film coated electrode. The ZnO and Cu-NPs were electrochemically deposited onto indium tin oxide (ITO) coated glass electrode and glassy carbon electrode (GCE) by layer-by-layer. In result, Cu-NPs/ZnO composite film topography was characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM). respectively. SEM and AFM confirmed the presence of nanometer sized Cu-NPs/ZnO composite particles on the electrode surface. In addition, X-ray diffraction pattern revealed that Cu-NPs and ZnO films were attached onto the electrode surface. Indeed, the Cu-NPs/ZnO composite modified electrode showed excellent electrocatalytic activity for glucose oxidation in alkaline (0.1 M NaOH) solution. Further, we utilized the Cu-NPs/ZnO composite modified electrode as an electrochemical sensor for detection of glucose. This glucose sensor showed a linear relationship in the range from 1 x 10(-6) M to 1.53 x 10(-3) M and the detection limit (S/N = 3) was found to be 2 x 10(-7) M. The Cu-NPs/ZnO composite as a non-enzymatic glucose sensor presents a number of attractive features such as high sensitivity, stability, reproducibility, selectivity and fast response. The applicability of the proposed method to the determination of glucose in human urine samples was demonstrated with satisfactory results. (C) 2009 Elsevier B.V. All rights reserved.