Recent advances in site-directed spin labeling of proteins
Recent advances in site-directed spin labeling of proteins
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DOI：
10.1016/s0959-440x(98)80158-9
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发表时间：
1998-10-01
影响因子：
6.8
通讯作者：
Lietzow, MA
中科院分区：
文献类型：
--
作者：
Hubbell, WL;Gross, A;Lietzow, MA
蛋白质定点自旋标记技术正经历一个快速的技术发展、应用和评价阶段，新的策略已被引入用于确定膜蛋白质形貌、静电势、蛋白质在膜表面的取向和残基间距离，新的应用包括β链的研究、利用自旋-自旋相互作用的结构作图、可溶性蛋白质的结构域运动和许多膜和可溶性蛋白质的广泛结构分析。
Site-directed spin labeling of proteins is experiencing a phase of rapid technical evolution, application and evaluation, New strategies have been introduced for determining membrane protein topography, electrostatic potentials, the orientation of proteins at membrane surfaces and inter-residue distances, New applications include studies of beta strands, structure mapping using spin-spin interactions, domain motions in soluble proteins and extensive structural analysis of a number of membrane and soluble proteins.