Distress reduction from a psychological intervention contributes to improved health for cancer patients
Distress reduction from a psychological intervention contributes to improved health for cancer patients
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DOI：
10.1016/j.bbi.2007.03.005
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发表时间：
2007-10-01
影响因子：
15.1
通讯作者：
Carson, William E., III
中科院分区：
文献类型：
--
作者：
Andersen, Barbara L.;Farrar, William B.;Carson, William E., III
目的.心理干预在减轻癌症患者的情绪困扰方面是有效的。然而，目前尚不清楚心理上的改善是否反过来与健康状况的改善有关。一项临床试验测试了对癌症患者的心理干预是否可以做到这一点，并测试了两种实现更好健康的途径：（a）减少患者的情绪困扰，和/或（B）增强他们的功能性免疫力。方法.术后，227例乳腺癌患者被随机分配至仅干预或评估研究组。在小组中进行，每周提供干预会议，持续4个月，然后每月进行一次，持续8个月。测量包括在基线、4个月和12个月时收集的心理（痛苦）、生物（免疫）和健康结果（表现状态和患者行为学评价，包括癌症治疗的毒性、实验室值）。结果路径模型显示，干预参与直接改善健康（p
Purpose. Psychological interventions are efficacious in reducing emotional distress for cancer patients. However, it is not clear whether psychological improvements are, in turn, related to improved health. A clinical trial tests whether a psychological intervention for cancer patients can do so, and also tests two routes to achieve better health: (a) reducing patients' Emotional Distress, and/or (b) enhancing their functional immunity. Methods. Post-surgery, 227 breast cancer patients were randomized to intervention or assessment only Study Arms. Conducted in small groups, intervention sessions were offered weekly for 4 months and followed by monthly sessions for 8 months. Measures included psychological (distress), biological (immune), and health outcomes (performance status and evaluations of patient's symptomatology, including toxicity from cancer treatment, lab values) collected at baseline, 4 months, and 12 months. Results. A path model revealed that intervention participation directly improved health (p